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Roxane - her name Roshanak means “little star” - was the daughter of a Sogdian nobleman named Oxyartes (Vaxšuvadarva), who defended a mountain fortress against the invading army of the Macedonian king Alexander the Great (327). When the fortress was captured, the sixteen year old woman was among the prisoners of war .
At that stage of his campaign in the Achaemenid empire, it had become obvious that Alexander could not control his conquests without doing concessions to the native population. He had to show respect to their customs if he wanted their loyalty. In the years 330-327, we see Alexander appointing Persians in important functions, dress himself like an Iranian nobleman, introduce the oriental court ritual (proskynesis). Marrying a local princess was a logical step.