Amlodipine CYP

3D Model

Model of the Calcium Channel inhibitor Amlodipine bound to the cytochrome CYP 2B6 created from the x-ray crystal structure 3UA5 from the RSCB Protein Data Bank. Original work from Manish B. Shah, P. Ross Wilderman, Jaime Pascual, Qinghai Zhang, C. David Stout, and James R. Halpert, “Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine Molecules”. Biochemistry (2012) 51(37), pp. 7225-7238.