Atorvastatin (Lipitor) & Mevastatin (Compactin)3D Model
Atorvastatin (Lipitor) & Mevastatin (Compactin)
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More model informationSide-by-side comparison of the structures of a Type II and Type I statins to highlight the structural similarities and differences. The Atorvastatin structure was extracted from the x-ray crystal structure 1HWK on the RSCB Protein Databank and the Mevastatin from 1HW8. Both crystal structures deposited in the PSCB PDB from Structural mechanism for statin inhibition of HMG-CoA reductase. Istvan, E.S., Deisenhofer, J. (2001) Science 292: pp. 1160-1164.
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Dec 23rd 2019
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