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Diverticular disease consists of two conditions: diverticulosis and diverticulitis. Diverticulosis is the formation of several tiny pockets, or diverticula, in the lining of the bowel. Diverticula, which can range from pea-size to much larger, are formed by increased pressure from gas, waste, or liquid on weakened spots of the intestinal walls. Diverticula can form while straining during a bowel movement, as during constipation. They are most common in the lower portion of the large intestine (the sigmoid colon).