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Goblet Cell 3D Model
Goblet cells are specialized epithelial cells that line the gastrointestinal and respiratory tract. They secrete mucin, which are stored in secretory vesicles in the apical surface, and release it through merocrine secretion. Mucin is the principal compontent of mucus, which protects the mucus membrances by catching debris and pathogens. Goblet cells also have microvilli on the apical surface to increase the surface area. They have a “goblet-like-shape” with a concentration of vesicles on the top and gradually becoming slimmer towards the basal side where other organelles reside. Goblet cells continue to produce mucin to replace the existing mucus layer. Mucin secretion is also stimulated by other factors such as allergens, bacteria, or irritants.