Human TPI

3D Model

The human triose phosphate isomerase – a glycolytic enzyme that catalyses the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, an essential reaction in the glycolytic pathway. It is a homodimeric enzyme that is found in all living organisms in which it has been looked for. Each subunit contains about 250 amino acid residues, 8 alpha-helices on the outside and 8 beta-strands on the inside, a structural motif commonly known as a TIM barrel.