Plant-made Polio type 3Your model is disabled. For more details go to Edit properties3D Model
Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine.
Structural analysis of the stabilized mutant at 3.6 Å resolution by cryo-electron microscopy and single-particle reconstruction reveals a structure almost indistinguishable from wild-type PV3.Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice transgenic for the human poliovirus receptor.
The original particle and additional info can be found here: http://www.rcsb.org/structure/5O5B