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More model informationCDX2 is a transcription factor that has key role in regulating the transcription of multiple genes expressed in the intestinal epithelium. It’s able to active or repress gene expression as needed. It’s also essential for both the proliferation and differentiation of cells in the intestinal track in early embryonic development. This model shows some interesting factors about CDX2 includes the DNA binding sites, the N-terminal, the bending of DNA for DNA-protein interaction and also the role of water molecules in the protein-DNA interface. Reference: https://www.genecards.org/cgi-bin/carddisp.pl?gene=CDX2 https://elifesciences.org/articles/32963#fig2 https://www.rcsb.org/structure/6ES2
Mar 24th 2022
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