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More model informationHIV-1 protease is a dimeric enzyme that is responsible for the proliferation of retroviruses and the process of gag and gag-pol during virion maturation. This dimeric organisation presents some important ligands that interact in this protein such as the main inhibitor and active sites that coordinates the molecule to successfully work in order to develop the anti-AIDS drugs to slow down the progression of the HIV virus.
In this diagram, HIV-1 protease shows some key features of the protein such as the inhibitor to help develop a drug called saquinavir to treat HIV/AIDS.
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