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More model informationIsolated initially from the bacteria Ideonella sakaiensis, PET hydrolase (PETase) preferentially breaks the world’s most utilised plastic into bite-sized chunks. Degradation of polyethylene terephthalate (PET) provides I. sakaiensis with a carbon source with which to sustain itself, and helps clean up the Earth at the same time. Discovery of PETase in 2016 has opened up exciting possibilities for bioremediation of the damage being done to our precious marine and terrestrial environments as PET gradually degrades over decades, and suggests a new path for efficient recycling of common consumer products. Shown here is the A131 mutant, with HEMT (hydroxyethyl methyl terephthalate) substrate homologue.
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